Vaccine Victory: How COVID-19 shots slash all-cause mortality and outshine misinformation
A growing body of research indicates that COVID-19 vaccines not only reduce the incidence of infection but also significantly decrease all-cause mortality among vaccinated individuals compared to those who are unvaccinated.
Understanding the role of observed vs. expected observational studies in vaccine safety
Vaccines are a cornerstone of public health, providing protection against many infectious diseases. Vaccine safety monitoring is an important aspect of ensuring that vaccines are safe and effective. In this blog, we will discuss observed versus (vs.) expected observational studies, which are commonly used tools to actively monitor vaccine safety.
Md (Sami) Samiullah PhD, MSc, BSc(Honours)
Gonzalo Sepúlveda MSc, BSc(Environmental Science)
The next generation of pharmacovigilance
Historically, much of the safety assessment of a new vaccine was deferred to post-introduction. Safety assessments within pre-approval clinical trials tended to be separate from post-approval Real-World evidence (RWE). There were barriers to implementing a vaccine lifecycle approach, including a disconnect between separate teams and staff for pre- versus post-approval. Applicability in low- and middle-income countries (LMICs) and high-income countries (HICs) was also limited. In fact, LMICs were often missing large administrative datasets.
Misinformation immunity, I’ll have some of that please
The surge and rapid dissemination of misinformation means it is essential that vaccine communications employ the most effective techniques first time, every time. Debunking is one of these, provision of correct information can be done by experts and non-experts ‘on-the-spot’.